INT139941

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Context Info
Confidence 0.70
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.21
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ugt1a1) enzyme binding (Ugt1a1)
Anatomy Link Frequency
1A6 1
spinal cord 1
Ugt1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 2 96.36 Very High Very High Very High
Paracetamol 2 94.80 High High
Spinal cord 13 94.72 High High
allodynia 21 50.00 Quite Low
Hyperalgesia 2 50.00 Quite Low
B1 receptor 91 45.92 Quite Low
antagonist 13 44.96 Quite Low
bradykinin 13 41.28 Quite Low
imagery 1 39.28 Quite Low
Inflammation 5 10.00 Low Low
Disease Link Frequency Relevance Heat
Acute-phase Reaction 1 75.00 Quite High
Frailty 2 65.80 Quite High
Pain 6 64.28 Quite High
Stress 33 50.00 Quite Low
Neuropathic Pain 26 50.00 Quite Low
Pressure And Volume Under Development 19 50.00 Quite Low
Insulin Resistance 13 50.00 Quite Low
Hyperalgesia 2 50.00 Quite Low
Diabetes Mellitus 17 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemistry was used to localize the B1 and TRPV-1 receptors within the spinal cord.
Localization (localize) of B1 in spinal cord
1) Confidence 0.70 Published 2006 Journal Spine Section Body Doc Link 17108828 Disease Relevance 0.13 Pain Relevance 0
Real-Time PCR was used to determine mRNA levels of UGT1A1, 1A6, 2B1, and 2B3 in the harvested organs.
Spec (determine) Localization (levels) of UGT1A1 in 1A6
2) Confidence 0.67 Published 2008 Journal Drug Metab Lett Section Abstract Doc Link 19356101 Disease Relevance 0.07 Pain Relevance 0.25
Density and distribution of kinin B1 receptors by autoradiography
Localization (receptors) of B1
3) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935380 Disease Relevance 0 Pain Relevance 0.08

General Comments

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