INT140002

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurite 4
Wld (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 4 98.52 Very High Very High Very High
induced neuropathy 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 2 94.76 High High
Injury 2 85.76 High High
Wallerian Degeneration 2 83.00 Quite High
Neuropathic Pain 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The overexpression of WldS delayed the neurite degeneration by vincristine, whereas that of Nmnat1 did not delay it much.
Positive_regulation (overexpression) of Gene_expression (overexpression) of WldS in neurite associated with vincristine
1) Confidence 0.56 Published 2007 Journal Neurosci. Lett. Section Abstract Doc Link 17113230 Disease Relevance 0.33 Pain Relevance 0.16
We generated WldS or Nmnat1-overexpressing Neuro2A cell lines, in which neuronal differentiation including neurite elongation can be induced by retinoic acid.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of WldS in neurite
2) Confidence 0.41 Published 2007 Journal Neurosci. Lett. Section Abstract Doc Link 17113230 Disease Relevance 0.33 Pain Relevance 0.16

General Comments

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