INT140014

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.58
Pain Relevance 2.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp) extracellular space (Avp) extracellular region (Avp)
cytoplasm (Chkb) response to stress (Avp) signal transducer activity (Avp)
Avp (Rattus norvegicus)
Chkb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 26 100.00 Very High Very High Very High
antagonist 8 99.10 Very High Very High Very High
Central grey 22 98.12 Very High Very High Very High
Dynorphin 4 97.22 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 22 98.12 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Radioimmunoassy results showed that AVP increased leucine-enkephalin (L-Ek), methionine-enkephalin (M-Ek), beta-endorphin (beta-Ep) rather than dynorphin A(1-13) (DynA(1-13)) concentrations in PAG slice culture liquid, and V(2) receptor antagonist: d(CH(2))(5)[D-Ile(2), Ile(4), Ala(9)-NH(2)]AVP decreased L-Ek, M-Ek and beta-Ep, not DynA(1-13) concentrations in PAG slice culture liquid in a dose-dependent manner, but V(1) receptor antagonist: d(CH(2))(5)Tyr(Me)AVP did not change these peptide concentrations in PAG slice culture liquid.
AVP Neg (not) Negative_regulation (decreased) of M-Ek associated with dynorphin, antagonist, enkephalin and central grey
1) Confidence 0.04 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 17113946 Disease Relevance 0.79 Pain Relevance 1.43
Radioimmunoassy results showed that AVP increased leucine-enkephalin (L-Ek), methionine-enkephalin (M-Ek), beta-endorphin (beta-Ep) rather than dynorphin A(1-13) (DynA(1-13)) concentrations in PAG slice culture liquid, and V(2) receptor antagonist: d(CH(2))(5)[D-Ile(2), Ile(4), Ala(9)-NH(2)]AVP decreased L-Ek, M-Ek and beta-Ep, not DynA(1-13) concentrations in PAG slice culture liquid in a dose-dependent manner, but V(1) receptor antagonist: d(CH(2))(5)Tyr(Me)AVP did not change these peptide concentrations in PAG slice culture liquid.
AVP Neg (not) Negative_regulation (decreased) of L-Ek associated with dynorphin, antagonist, enkephalin and central grey
2) Confidence 0.04 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 17113946 Disease Relevance 0.79 Pain Relevance 1.43

General Comments

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