INT140015

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.63
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 4
Disease Relevance 3.48
Pain Relevance 6.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Avp, Penk) signal transduction (Avp) extracellular space (Avp)
response to stress (Avp) signal transducer activity (Avp)
Avp (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central grey 42 100.00 Very High Very High Very High
Enkephalin 40 100.00 Very High Very High Very High
Pain 8 100.00 Very High Very High Very High
Dynorphin 4 98.92 Very High Very High Very High
Neurotransmitter 10 97.80 Very High Very High Very High
Pain threshold 6 97.12 Very High Very High Very High
antagonist 14 96.48 Very High Very High Very High
Antinociceptive 2 91.92 High High
opiate 6 88.24 High High
narcan 2 87.64 High High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 42 100.00 Very High Very High Very High
Pain 12 98.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data suggest that AVP enhances PAG synthesizing and secreting enkephalin and endorphin rather than dynorphin through V(2) receptors.
AVP Positive_regulation (enhances) of Localization (secreting) of enkephalin associated with dynorphin, enkephalin and central grey
1) Confidence 0.63 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 17113946 Disease Relevance 0.85 Pain Relevance 1.38
Arginine vasopressin induces periaqueductal gray release of enkephalin and endorphin relating to pain modulation in the rat.
Arginine vasopressin Positive_regulation (induces) of Localization (release) of enkephalin associated with pain, enkephalin and central grey
2) Confidence 0.42 Published 2007 Journal Regul. Pept. Section Title Doc Link 17341433 Disease Relevance 0.83 Pain Relevance 1.74
Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.
Arginine vasopressin Positive_regulation (enhances) of Localization (secretion) of enkephalin associated with enkephalin and central grey
3) Confidence 0.37 Published 2006 Journal Brain Res. Bull. Section Title Doc Link 17113946 Disease Relevance 0.77 Pain Relevance 1.64
The data suggested that AVP in PAG could induce the local release of enkephalin and endorphin rather than dynophin, OXT and classical neurotransmitters to participate in pain modulation.
AVP Positive_regulation (induce) of Localization (release) of enkephalin associated with pain, neurotransmitter, enkephalin and central grey
4) Confidence 0.32 Published 2007 Journal Regul. Pept. Section Abstract Doc Link 17341433 Disease Relevance 1.02 Pain Relevance 1.87

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox