INT140057

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk9) mitochondrion (Mapk9) nucleus (Mapk9)
kinase activity (Mapk9) transcription factor binding (Mapk9) cytoplasm (Mapk9)
Mapk9 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 1 98.40 Very High Very High Very High
Inflammation 4 75.00 Quite High
COX-2 inhibitor 1 48.96 Quite Low
cINOD 1 47.72 Quite Low
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 98.04 Very High Very High Very High
Repression 1 78.76 Quite High
Sepsis 1 44.60 Quite Low
Infection 1 40.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In support of this concept, we found, using inhibitors of Jun kinase and NF-kappaB p50 nuclear localization, that COX-2 gene transcription was completely dependent on phospho-c-Jun plus p50 at 6 h after LPS treatment but was only partially dependent on the combination of these factors at later treatment times.
Negative_regulation (using) of Negative_regulation (inhibitors) of Jun kinase
1) Confidence 0.15 Published 2006 Journal J. Immunol. Section Abstract Doc Link 17114486 Disease Relevance 0.31 Pain Relevance 0.12

General Comments

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