INT140122

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Context Info
Confidence 0.62
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.16
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Nefl) locomotion (Nefl) response to stress (Nefl)
Anatomy Link Frequency
spinal cords 1
Nefl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 6 87.84 High High
Spinal cord 39 85.52 High High
Calcitonin gene-related peptide 2 75.76 Quite High
induced neuropathy 2 73.04 Quite High
Serotonin 3 39.52 Quite Low
Enkephalin 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Poisoning 2 91.52 High High
Neuropathic Pain 2 73.04 Quite High
Frailty 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 2 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Shock 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the meantime, the mRNA levels of NF-H, NF-M, and NF-L in spinal cords were quantified using reverse transcriptase-polymerase chain reaction.
Transcription (levels) of NF-L in spinal cords
1) Confidence 0.62 Published 2006 Journal Neurochem. Res. Section Abstract Doc Link 17120161 Disease Relevance 0.07 Pain Relevance 0.11
Furthermore, the levels of mRNA expression of NF-H, NF-M, and NF-L genes were elevated consistently in CS(2)-treated groups.
Transcription (expression) of NF-L
2) Confidence 0.62 Published 2006 Journal Neurochem. Res. Section Abstract Doc Link 17120161 Disease Relevance 0.09 Pain Relevance 0.08
Among the unique DE genes displayed in Table 1, a representative subset of seven genes were chosen for micorarray validation with real time reverse transcription PCR (real time RT-PCR); MN>dCIN: Nefl, Calcb, Kcna1, 5HT3r, VAChT; dCIN>MN: Ox2r, Viaat.
Transcription (transcription) of Nefl
3) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2566599 Disease Relevance 0 Pain Relevance 0.08

General Comments

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