INT140187

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itga2) plasma membrane (Itga2) nucleus (Itga2)
Anatomy Link Frequency
cartilage 1
Itga2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 2 99.26 Very High Very High Very High
Osteoarthritis 4 93.60 High High
Snapping jaw 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Osteoarthritis 4 93.60 High High
Temporomandibular Joint Syndrome 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also found that the overexpression of matrix metalloproteinase 13 (Mmp-13) was probably due to the up-regulation of a collagen receptor, discoidin domain receptor 2 (Ddr2), which was responsible for knee cartilage degeneration in mutant mice.
Positive_regulation (up-regulation) of collagen receptor in cartilage associated with metalloproteinase
1) Confidence 0.18 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.34 Pain Relevance 0.30

General Comments

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