INT140235

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Context Info
Confidence 0.46
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADRBK1, MC1R) pigmentation (MC1R) cytosol (ADRBK1)
signal transduction (ADRBK1) aging (ADRBK1) signal transducer activity (MC1R)
ADRBK1 (Homo sapiens)
MC1R (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 10 100.00 Very High Very High Very High
agonist 1 85.68 High High
Disease Link Frequency Relevance Heat
Skin Cancer 4 95.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show that in contrast with this dual specificity for desensitization, GRK6 but not GRK2 mediated MC1R internalization.
GRK2 Positive_regulation (mediated) of MC1R Binding (internalization) of associated with melanocortin 1 receptor
1) Confidence 0.46 Published 2007 Journal J. Biol. Chem. Section Abstract Doc Link 17130136 Disease Relevance 0.31 Pain Relevance 0.68

General Comments

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