INT140279

Context Info Confidence 0.24 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.71 Pain Relevance 0.93

molecular_function (Grina) cellular_component (Grina) biological_process (Grina)

Anatomy Link Frequency spinal cord 1 Grina (Mus musculus)

Pain Link Frequency Relevance Heat Glutamate receptor 3 100.00 Spinal cord 5 98.52 hypoalgesia 1 95.68 substance P 1 91.96 Glutamate 1 85.88 adenocard 7 85.68 antagonist 1 81.52 Inflammation 1 79.16 MU agonist 1 54.84 Analgesic 1 52.92

Disease Link Frequency Relevance Heat Targeted Disruption 4 99.08 Hypoalagesia 1 95.68 Nociception 4 89.08 INFLAMMATION 1 79.16 Pain 1 49.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The decrease in NMDA glutamate receptor binding may reflect reduced peripheral sensory input to the spinal cord during development and could relate to the hypoalgesia in this genotype.

NMDA glutamate receptor Binding (binding) of in spinal cord associated with glutamate receptor, hypoalgesia and spinal cord

1) Confidence 0.24 Published 2007 Journal Pain Section Abstract Doc Link 17134834 Disease Relevance 0.71 Pain Relevance 0.93

General Comments

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