INT140298

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.10
Pain Relevance 2.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dorsal horn 1
veins 1
Myo5c (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 10 99.96 Very High Very High Very High
Inflammation 40 98.48 Very High Very High Very High
primary afferent fibers 1 98.28 Very High Very High Very High
Snapping jaw 38 97.96 Very High Very High Very High
lidocaine 6 96.60 Very High Very High Very High
Pain 52 96.04 Very High Very High Very High
Central grey 2 87.92 High High
Lasting pain 16 83.68 Quite High
Central nervous system 3 83.04 Quite High
central pain 4 81.16 Quite High
Disease Link Frequency Relevance Heat
Injury 50 99.12 Very High Very High Very High
INFLAMMATION 48 98.48 Very High Very High Very High
Nociception 22 98.24 Very High Very High Very High
Temporomandibular Joint Syndrome 38 97.96 Very High Very High Very High
Pain 75 96.04 Very High Very High Very High
Urological Neuroanatomy 2 87.92 High High
Hyperalgesia 84 76.88 Quite High
Tendon Injuries 22 64.52 Quite High
Hypersensitivity 20 50.00 Quite Low
Tendinopathy 14 40.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings suggest that PRO is involved in the enhancement of Vc activity through direct activation of the primary afferent fibers innervating veins, resulting in pain induction during infusion.
Positive_regulation (enhancement) of Vc in veins associated with pain and primary afferent fibers
1) Confidence 0.03 Published 2007 Journal Exp Brain Res Section Abstract Doc Link 17136530 Disease Relevance 0.39 Pain Relevance 0.75
There were no significant increases in Fos-LI in the Vc-C1 contralateral to the injury (not shown).
Neg (no) Positive_regulation (increases) of Vc-C1 associated with injury
2) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2914030 Disease Relevance 0.48 Pain Relevance 0.39
We identified neuronal activation in the Vc-C1 dorsal horn, the first relay of trigeminal nociceptive input, after TASM injury.
Positive_regulation (activation) of Vc-C1 in dorsal horn associated with nociception, injury and dorsal horn
3) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2914030 Disease Relevance 1.23 Pain Relevance 1.02

General Comments

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