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Context Info
Confidence 0.31
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.03
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (NALCN)
NALCN (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 1 98.68 Very High Very High Very High
agonist 6 90.60 High High
Glutamate receptor 1 88.56 High High
alcohol 25 85.52 High High
Central nervous system 27 83.36 Quite High
Neurotransmitter 7 82.92 Quite High
excitatory amino acid 1 82.24 Quite High
Glutamate 3 76.60 Quite High
gABA 16 75.80 Quite High
antagonist 4 69.04 Quite High
Disease Link Frequency Relevance Heat
Affective Disorder 66 99.32 Very High Very High Very High
Poisoning 2 98.24 Very High Very High Very High
Acidosis 1 96.80 Very High Very High Very High
Pathologic Processes 1 83.12 Quite High
Sleep Disorders 28 81.52 Quite High
Coma 2 80.72 Quite High
Alcohol Addiction 29 68.60 Quite High
Delirium 9 63.92 Quite High
Respiratory Failure 5 61.08 Quite High
Attention Deficit Hyperactivity Disorder 5 42.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In figure 3 the log maximum length of time reported for single ion channels to transition through an open and closed cycle and the log of the duration of evoked whole cell potentials were plotted versus the number of ion channels.
Positive_regulation (reported) of ion
1) Confidence 0.31 Published 2006 Journal Theor Biol Med Model Section Body Doc Link PMC1360660 Disease Relevance 0 Pain Relevance 0
Transient receptor potential vanilloid (TRPV1), representing ion channel family, is activated in human and animal organism by capsaicin and some other factors such as heat, acidosis, and ion dysbalance.
Positive_regulation (activated) of ion associated with acidosis and qutenza
2) Confidence 0.07 Published 2006 Journal Eksp Klin Farmakol Section Abstract Doc Link 17153968 Disease Relevance 0.18 Pain Relevance 0.17
Ethanol is thought to inhibit the NMDA-activated ion current by a novel type of interaction with a hydrophobic site that is associated with the NMDA channel.
Positive_regulation (activated) of ion
3) Confidence 0.04 Published 2000 Journal Crit Care Section Body Doc Link PMC137331 Disease Relevance 0.53 Pain Relevance 0.83
Since negative ion generators have been reported to be effective in treatment of SAD [14], a "credible placebo" design similar to that of Eastman and colleagues [4], in which an inactivated negative ion generator was used as a "no light" control condition, was employed.
Positive_regulation (effective) of ion associated with affective disorder
4) Confidence 0.02 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC1971065 Disease Relevance 0.31 Pain Relevance 0

General Comments

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