INT140514

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Pacsin2) cytosol (Pacsin2) cytoplasmic membrane-bounded vesicle (Pacsin2)
cytoplasm (Pacsin2)
Anatomy Link Frequency
spinal cord 1
Pacsin2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 7 99.68 Very High Very High Very High
opioid receptor 7 92.96 High High
Kappa opioid receptor 3 91.28 High High
Neuropathic pain 5 87.12 High High
agonist 3 84.68 Quite High
antinociception 2 82.08 Quite High
Morphine 2 79.92 Quite High
Enkephalin 1 73.48 Quite High
withdrawal 2 62.56 Quite High
Hyperalgesia 1 56.24 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 5 87.12 High High
Hyperalgesia 1 56.24 Quite High
Peripheral Neuropathy 1 49.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under these conditions, immunoblotting showed a robust increase in phosphorylated-cPKC immunoreactivity (p-cPKC-IR) in the spinal cord from chronic ethanol fed-rats, whereas phosphorylated-protein kinase A (PKA), dynamin II and G protein-coupled receptor kinase 2 (GRK2) were not affected in the spinal cord of ethanol-fed rats.
Neg (not) Regulation (affected) of dynamin II in spinal cord associated with spinal cord
1) Confidence 0.16 Published 2007 Journal Neuroscience Section Abstract Doc Link 17156932 Disease Relevance 0.35 Pain Relevance 1.69

General Comments

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