INT140515

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 10
Disease Relevance 0.63
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

TSPAN33 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 21 91.28 High High
Adalimumab 3 50.00 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Confusion 9 92.16 High High
Obesity 9 76.76 Quite High
Diabetes Mellitus 9 66.08 Quite High
Pain 2 50.00 Quite Low
Ovarian Hyperstimulation Syndrome 36 34.16 Quite Low
Disease 1 30.60 Quite Low
INFLAMMATION 1 30.24 Quite Low
Spontaneous Abortion 9 19.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, patients perceived the Pen to be easier to use and more convenient.
Positive_regulation (perceived) of Pen
1) Confidence 0.44 Published 2006 Journal Clin Ther Section Body Doc Link 17157117 Disease Relevance 0 Pain Relevance 0
In total, 24.9% of patients with prior experience of daily injections with FSH had previously used the reusable follitropin beta pen.


Positive_regulation (reusable) of pen
2) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.08 Pain Relevance 0
Patients who had used both pen devices scored many attributes of the prefilled follitropin alfa pen more favourably than those of the reusable follitropin beta pen, including the device storage, device use and dose preparation [15].
Positive_regulation (reusable) of pen
3) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.09 Pain Relevance 0.05
A study of patients undergoing ART at an Australian centre compared the prefilled follitropin alfa pen with previous experience of the reusable follitropin beta pen [15,16].
Positive_regulation (prefilled) of pen
4) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.07 Pain Relevance 0.06
In total, 24.9% of patients with prior experience of daily injections with FSH had previously used the reusable follitropin beta pen.


Positive_regulation (used) of pen
5) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.08 Pain Relevance 0
Patients who had used both pen devices scored many attributes of the prefilled follitropin alfa pen more favourably than those of the reusable follitropin beta pen, including the device storage, device use and dose preparation [15].
Positive_regulation (attributes) of pen
6) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.09 Pain Relevance 0.05
A greater proportion of patients in the group using the prefilled follitropin alfa pen found the pen very easy to handle, and quicker to learn to use and prepare for injection than those using the reusable follitropin beta pen.
Positive_regulation (reusable) of pen
7) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0 Pain Relevance 0.13
This was significantly more than the proportion of participants who chose the reusable follitropin beta pen as their preferred device (24.5%; p < 0.0001).
Positive_regulation (reusable) of pen
8) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.07 Pain Relevance 0
Patients who had used both pen devices scored many attributes of the prefilled follitropin alfa pen more favourably than those of the reusable follitropin beta pen, including the device storage, device use and dose preparation [15].
Positive_regulation (prefilled) of pen
9) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.09 Pain Relevance 0.05
Results from comparative studies of the two available pen devices for injection of r-hFSH indicate a preference for the prefilled follitropin alfa pen among both patients and nurses [15,16].
Positive_regulation (preference) of pen
10) Confidence 0.21 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2949697 Disease Relevance 0.07 Pain Relevance 0.16

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