INT140538

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.70
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hearts 2
Bwk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 1 78.08 Quite High
antiarrhythmic agent 1 75.00 Quite High
sodium channel 2 73.96 Quite High
anesthesia 2 72.00 Quite High
Angina 1 36.40 Quite Low
ischemia 1 34.36 Quite Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 4 94.96 High High
Left Ventricular Dysfunction 2 92.40 High High
Heart Rate Under Development 2 89.76 High High
Diuresis 2 71.64 Quite High
Heart Arrhythmia 1 71.60 Quite High
Arrhythmia Under Development 3 61.20 Quite High
Syndrome 1 38.88 Quite Low
Channelopathies 1 37.24 Quite Low
Cv General 3 Under Development 1 36.40 Quite Low
Infarction 1 34.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute volume overload elevates TWA in normal canine hearts.
Positive_regulation (elevates) of TWA in hearts
1) Confidence 0.37 Published 2007 Journal J. Appl. Physiol. Section Abstract Doc Link 17158246 Disease Relevance 0.23 Pain Relevance 0.06
The objective of this study was to determine whether acute volume loading elevates T-wave alternans (TWA) in dogs with structurally normal hearts.
Spec (whether) Positive_regulation (elevates) of TWA in hearts
2) Confidence 0.37 Published 2007 Journal J. Appl. Physiol. Section Abstract Doc Link 17158246 Disease Relevance 0.33 Pain Relevance 0.07
There is also suggestive evidence that the proarrhythmic effects associated with cardiovascular and noncardiovascular agents may be disclosed by elevated levels of TWA.
Positive_regulation (elevated) of TWA
3) Confidence 0.27 Published 2010 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 20555232 Disease Relevance 0.13 Pain Relevance 0.15

General Comments

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