INT140606

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PMEL, ATF4) nucleoplasm (ATF4) endosome (PMEL)
Golgi apparatus (PMEL) endoplasmic reticulum (PMEL) DNA binding (ATF4)
PMEL (Homo sapiens)
ATF4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 77.80 Quite High
Disease Link Frequency Relevance Heat
Cancer 4 97.32 Very High Very High Very High
Stomach Cancer 2 92.12 High High
Hypoxia 1 86.12 High High
INFLAMMATION 1 77.56 Quite High
Apoptosis 5 76.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both the ATF4 and ATF6 pathways were activated by celecoxib, and suppression of ATF4 and ATF6 mRNA expression by small interfering RNA (siRNA) inhibited the celecoxib-dependent up-regulation of ORP150.
siRNA Negative_regulation (suppression) of Gene_expression (expression) of ATF4
1) Confidence 0.01 Published 2007 Journal Mol. Pharmacol. Section Abstract Doc Link 17167033 Disease Relevance 0.74 Pain Relevance 0.08

General Comments

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