INT14064

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Context Info
Confidence 0.22
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) nucleus (IRF6) DNA binding (IRF6)
cytoplasm (IRF6)
Anatomy Link Frequency
monocytes 2
IRF6 (Homo sapiens)
PCA (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 3 87.40 High High
Disease Link Frequency Relevance Heat
Depression 3 98.64 Very High Very High Very High
Leukemia 3 93.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, ethanol dose-dependently inhibited LPS-induced PCA in isolated human monocytes. 3.
Negative_regulation (inhibited) of LPS Positive_regulation (induced) of PCA in monocytes
1) Confidence 0.22 Published 1991 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 1685419 Disease Relevance 0.17 Pain Relevance 0.09
However, the induction of PCA by LPS was substantially inhibited when cells were pretreated with 1% ethanol (v/v) for 72 hr. 4.
Negative_regulation (inhibited) of LPS Positive_regulation (induction) of PCA
2) Confidence 0.22 Published 1991 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 1685419 Disease Relevance 0.18 Pain Relevance 0.08
Importantly, the percent reduction in LPS-induced PCA was much more pronounced than that in non-challenged PCA. 5.
Negative_regulation (reduction) of LPS Positive_regulation (induced) of PCA
3) Confidence 0.22 Published 1991 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 1685419 Disease Relevance 0.18 Pain Relevance 0.07

General Comments

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