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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNF, SLC6A4) endosome (SLC6A4) intracellular (TNF)
extracellular matrix organization (TNF) cytosol (SLC6A4) extracellular space (TNF)
Anatomy Link Frequency
bowel 2
TNF (Homo sapiens)
SLC6A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 97.60 Very High Very High Very High
spastic colon 2 95.64 Very High Very High Very High
Serotonin 2 75.00 Quite High
fluoxetine 1 70.44 Quite High
Inflammation 1 59.84 Quite High
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 2 96.52 Very High Very High Very High
Functional Bowel Disorder 2 95.64 Very High Very High Very High
INFLAMMATION 1 59.84 Quite High
Colitis 1 51.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By altering SERT expression, TNF-alpha and IFN-gamma could contribute to the altered motility and expression seen in vivo in ulcerative colitis or irritable bowel syndrome.
TNF-alpha Regulation (altering) of Gene_expression (expression) of SERT in bowel associated with inflammatory bowel disease and spastic colon
1) Confidence 0.40 Published 2007 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17170025 Disease Relevance 0.41 Pain Relevance 0.34

General Comments

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