INT140935

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 6
Disease Relevance 6.34
Pain Relevance 5.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cd40lg, Cd40) extracellular region (Cd40lg, Cd40) plasma membrane (Cd40lg, Cd40)
molecular_function (Cd40lg, Cd40) enzyme binding (Cd40)
Anatomy Link Frequency
T cell 6
Cd40lg (Rattus norvegicus)
Cd40 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 72 99.20 Very High Very High Very High
Sciatic nerve 6 79.52 Quite High
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 72 99.20 Very High Very High Very High
Immunization 12 91.12 High High
Disease 6 80.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evidently, B cells play a cooperative role via CD40L-CD40 interaction in T cell-mediated EAN of Lewis rats.
CD40L Binding (interaction) of CD40 in T cell associated with neuritis
1) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Abstract Doc Link 17188497 Disease Relevance 1.03 Pain Relevance 0.98
The results indicate that CD40L-CD40 interactions are involved in the initiation of the antigen-specific T cell responses associated with the generation and development of EAN, and may mediate autoantibody production in EAN.
CD40L Binding (interactions) of CD40 in T cell associated with neuritis
2) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Abstract Doc Link 17188497 Disease Relevance 1.13 Pain Relevance 1.04
B cells play a cooperative role via CD40L-CD40 interaction in T cell-mediated experimental autoimmune neuritis in Lewis rats.
CD40L Binding (interaction) of CD40 in T cell associated with experimental autoimmune neuritis and neuritis
3) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Title Doc Link 17188497 Disease Relevance 1.01 Pain Relevance 0.79
B cells play a cooperative role via CD40L-CD40 interaction in T cell-mediated experimental autoimmune neuritis in Lewis rats.
CD40L Binding (interaction) of CD40 in T cell associated with experimental autoimmune neuritis and neuritis
4) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Title Doc Link 17188497 Disease Relevance 1.01 Pain Relevance 0.79
The results indicate that CD40L-CD40 interactions are involved in the initiation of the antigen-specific T cell responses associated with the generation and development of EAN, and may mediate autoantibody production in EAN.
CD40L Binding (interactions) of CD40 in T cell associated with neuritis
5) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Abstract Doc Link 17188497 Disease Relevance 1.13 Pain Relevance 1.04
Evidently, B cells play a cooperative role via CD40L-CD40 interaction in T cell-mediated EAN of Lewis rats.
CD40L Binding (interaction) of CD40 in T cell associated with neuritis
6) Confidence 0.30 Published 2007 Journal Neurobiol. Dis. Section Abstract Doc Link 17188497 Disease Relevance 1.03 Pain Relevance 0.98

General Comments

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