INT141020

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh, Pomc) extracellular region (Crh, Pomc) cytoplasm (Crh, Pomc)
signal transduction (Pomc) generation of precursor metabolites and energy (Pomc) cell-cell signaling (Pomc)
Anatomy Link Frequency
anterior pituitary 4
Crh (Rattus norvegicus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 2 99.64 Very High Very High Very High
local anesthetic 6 78.96 Quite High
Disease Link Frequency Relevance Heat
Stress 2 85.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND AND OBJECTIVES: Corticotropin-releasing hormone (CRH) induces gene expression of proopiomelanocortin, a precursor protein of adrenocorticotropic hormone and beta-endorphin, by elevating intracellular cyclic adenosine 3',5'-monophosphate (cyclic AMP) level in anterior pituitary cells and immune cells.
CRH Positive_regulation (induces) of Gene_expression (expression) of beta-endorphin in anterior pituitary associated with adenocard
1) Confidence 0.05 Published 2007 Journal Reg Anesth Pain Med Section Abstract Doc Link 17196494 Disease Relevance 0.09 Pain Relevance 0.28
BACKGROUND AND OBJECTIVES: Corticotropin-releasing hormone (CRH) induces gene expression of proopiomelanocortin, a precursor protein of adrenocorticotropic hormone and beta-endorphin, by elevating intracellular cyclic adenosine 3',5'-monophosphate (cyclic AMP) level in anterior pituitary cells and immune cells.
Corticotropin-releasing hormone Positive_regulation (induces) of Gene_expression (expression) of beta-endorphin in anterior pituitary associated with adenocard
2) Confidence 0.05 Published 2007 Journal Reg Anesth Pain Med Section Abstract Doc Link 17196494 Disease Relevance 0.09 Pain Relevance 0.28

General Comments

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