INT141024

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.84
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
peripheral nerve 1
T-lymphocytes 1
TEX33 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 16 100.00 Very High Very High Very High
Inflammation 29 87.24 High High
Peripheral nervous system 10 74.80 Quite High
Central nervous system 8 54.88 Quite High
Demyelination 11 35.16 Quite Low
Sciatic nerve 7 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 16 100.00 Very High Very High Very High
Immunization 3 99.56 Very High Very High Very High
Syndrome 29 92.32 High High
Demyelinating Disease 25 87.80 High High
INFLAMMATION 27 87.24 High High
Disease 36 84.16 Quite High
Infection 6 65.12 Quite High
Chronic Inflammatory Demyelinating Polyradiculoneuropathy 10 63.12 Quite High
Neuropathy 6 50.00 Quite Low
Guillain-barre Syndrome 16 41.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of TNFalpha/LTalpha during EAN induced by active immunization with peripheral nerve myelin was examined by administering a recombinant soluble chimeric form of human TNF receptor 1 (TNFR1-IgG).
Positive_regulation (induced) of EAN in peripheral nerve associated with immunization
1) Confidence 0.05 Published 2007 Journal J. Neuroimmunol. Section Abstract Doc Link 17196669 Disease Relevance 0.44 Pain Relevance 0.14
Alternatively, EAN can be induced by adoptive transfer of activated P2-specific neuritogenic T-lymphocytes [11].
Positive_regulation (induced) of EAN in T-lymphocytes associated with neuritis
2) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2825213 Disease Relevance 1.40 Pain Relevance 0.69

General Comments

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