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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (ZNF404, TNF) extracellular matrix organization (TNF) DNA binding (ZNF404)
extracellular space (TNF) signal transduction (TNF) extracellular region (TNF)
Anatomy Link Frequency
T cells 2
ZNF404 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 3 89.60 High High
Endocannabinoid 1 87.28 High High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, we found that AM404 specifically inhibited both IL-2 and TNF-alpha gene transcription and TNF-alpha synthesis in CD3/CD28-stimulated Jurkat T cells in a FAAH independent way.
AM404 Negative_regulation (inhibited) of Transcription (transcription) of TNF-alpha in T cells
1) Confidence 0.01 Published 2007 Journal Biochem. Pharmacol. Section Abstract Doc Link 17196940 Disease Relevance 0 Pain Relevance 0.21

General Comments

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