INT141048

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF404, NFATC1) DNA binding (ZNF404, NFATC1) intracellular (ZNF404)
cytoplasm (NFATC1)
ZNF404 (Homo sapiens)
NFATC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 3 75.00 Quite High
Endocannabinoid 1 72.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that AM404 inhibited both the binding to DNA and the transcriptional activity of endogenous NFAT and the transcriptional activity driven by the over expressed fusion protein Gal4-NFAT (1-415).
AM404 Negative_regulation (inhibited) of NFAT Binding (binding) of
1) Confidence 0.01 Published 2007 Journal Biochem. Pharmacol. Section Abstract Doc Link 17196940 Disease Relevance 0 Pain Relevance 0.24

General Comments

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