INT141097

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Context Info
Confidence 0.48
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.28
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sftpa1) extracellular region (Sftpa1)
Sftpa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 8 97.16 Very High Very High Very High
Dismenorea 4 91.96 High High
Disease Link Frequency Relevance Heat
Premature Birth 4 92.68 High High
Dysmenorrhea 4 91.96 High High
Pre-term Labor 4 89.36 High High
Infection 4 88.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The addition of rough-type LPS to SFTPA1 blocked the interaction of SFTPA1 with its binding sites and the activation of MAPK1/3 and PTGS2 by SFTPA1.
SFTPA1 Binding (interaction) of
1) Confidence 0.48 Published 2007 Journal Biol. Reprod. Section Abstract Doc Link 17202387 Disease Relevance 0.31 Pain Relevance 0.14
This result was confirmed by biochemical approaches. [(125)I]-SFTPA1 bound to two myometrial cell proteins (55 and 210 kDa).
SFTPA1 Binding (bound) of
2) Confidence 0.48 Published 2007 Journal Biol. Reprod. Section Abstract Doc Link 17202387 Disease Relevance 0.32 Pain Relevance 0.11
Fluorescence microscopy showed that Texas Red-labeled SFTPA1 bound to myometrial cells.
SFTPA1 Binding (bound) of
3) Confidence 0.48 Published 2007 Journal Biol. Reprod. Section Abstract Doc Link 17202387 Disease Relevance 0.31 Pain Relevance 0.10
This interaction was dependent on the integrity of the collagenlike domain of SFTPA1.
SFTPA1 Binding (integrity) of
4) Confidence 0.37 Published 2007 Journal Biol. Reprod. Section Abstract Doc Link 17202387 Disease Relevance 0.33 Pain Relevance 0.13

General Comments

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