INT141212

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR6) signal transducer activity (HTR6)
HTR6 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 100.00 Very High Very High Very High
agonist 4 95.44 Very High Very High Very High
Serotonin 6 90.04 High High
fluoxetine 1 70.96 Quite High
sSRI 2 59.20 Quite High
Disease Link Frequency Relevance Heat
Obesity 4 87.64 High High
Appetite Loss 3 87.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, 5-HT6 receptor antagonists such as PRX-07034 and BVT74316 have been shown to potently reduce food intake and bodyweight gain in rodent models and have recently entered clinical trials.
Negative_regulation (reduce) of 5-HT6 associated with antagonist
1) Confidence 0.41 Published 2007 Journal Drugs Section Abstract Doc Link 17209663 Disease Relevance 0.39 Pain Relevance 0.44

General Comments

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