INT141244

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fos, Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
aging (Fos) Golgi apparatus (Prkaca) DNA binding (Fos)
Anatomy Link Frequency
heart 1
Fos (Rattus norvegicus)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
withdrawal 7 99.64 Very High Very High Very High
Morphine 10 99.42 Very High Very High Very High
noradrenaline 5 83.12 Quite High
narcan 4 75.00 Quite High
adenocard 1 75.00 Quite High
Opioid 1 67.00 Quite High
addiction 1 60.16 Quite High
Disease Link Frequency Relevance Heat
Opiate Addiction 1 67.44 Quite High
Attention Deficit Hyperactivity Disorder 1 41.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings indicate that an up-regulated PKA-dependent transduction pathway might contribute to the activation of the cardiac catecholaminergic neurons in response to morphine withdrawal and suggest that Fos is not a target of PKA at heart levels.
Fos Neg (not) Regulation (target) of PKA in heart associated with withdrawal and morphine
1) Confidence 0.18 Published 2007 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 17216288 Disease Relevance 0.07 Pain Relevance 1.24

General Comments

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