INT141254

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 1.37
Pain Relevance 3.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) signal transduction (Ngf) extracellular space (Ngf)
aging (Ngf) extracellular region (Ngf) plasma membrane (Trpv1)
Anatomy Link Frequency
nerve 2
Ngf (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 24 100.00 Very High Very High Very High
nociceptor 18 100.00 Very High Very High Very High
Pain 12 100.00 Very High Very High Very High
qutenza 3 99.76 Very High Very High Very High
IPN 3 99.64 Very High Very High Very High
vanilloid receptor subtype 1 3 97.20 Very High Very High Very High
Thermal hyperalgesia 3 90.56 High High
Inflammation 6 86.44 High High
Disease Link Frequency Relevance Heat
Inflammatory Pain 3 99.64 Very High Very High Very High
Pain 3 91.44 High High
Hyperalgesia 3 90.56 High High
Injury 6 86.72 High High
INFLAMMATION 6 86.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because NGF is a key modulator of inflammatory pain, we examined the effect of NGF on rTRPV1 transcription in PC12 cells.
NGF Spec (examined) Regulation (effect) of Transcription (transcription) of rTRPV1 associated with nerve growth factor and ipn
1) Confidence 0.53 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17217411 Disease Relevance 0.48 Pain Relevance 1.11
Transcription of rat TRPV1 utilizes a dual promoter system that is positively regulated by nerve growth factor.
nerve growth factor Regulation (regulated) of Transcription (Transcription) of TRPV1 in nerve associated with nerve growth factor and nociceptor
2) Confidence 0.45 Published 2007 Journal J. Neurochem. Section Title Doc Link 17217411 Disease Relevance 0.42 Pain Relevance 1.53
NGF positively regulated transcriptional activity of both rTRPV1 promoter regions in PC12 cells.
NGF Regulation (regulated) of Transcription (activity) of rTRPV1 associated with nerve growth factor
3) Confidence 0.23 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17217411 Disease Relevance 0.47 Pain Relevance 1.11

General Comments

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