INT141308

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnk4)
Kcnk4 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 6 98.80 Very High Very High Very High
potassium channel 2 94.28 High High
antidepressant 2 92.16 High High
fluoxetine 2 90.24 High High
Disease Link Frequency Relevance Heat
Schizophrenia 4 99.56 Very High Very High Very High
Depression 6 98.80 Very High Very High Very High
Mental Disorders 2 98.48 Very High Very High Very High
Stress 2 96.80 Very High Very High Very High
Hallucination 2 93.32 High High
Cognitive Disorder 2 90.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antipsychotics inhibit TREK but not TRAAK channels.
Negative_regulation (inhibit) of TRAAK
1) Confidence 0.41 Published 2007 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 17222806 Disease Relevance 0.63 Pain Relevance 0.27
The inactivation of the TREK-1 but not the TRAAK channel in mice results in a depression-resistant phenotype.
Negative_regulation (inactivation) of TRAAK associated with depression
2) Confidence 0.36 Published 2007 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 17222806 Disease Relevance 0.63 Pain Relevance 0.30

General Comments

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