INT141338

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 3 Disease Relevance 1.75 Pain Relevance 0.59

mitochondrion (Bsg)

Anatomy Link Frequency stroma 1 stellate cells 1 Bsg (Rattus norvegicus)

Pain Link Frequency Relevance Heat metalloproteinase 9 100.00 Chronic pancreatitis 6 85.32

Disease Link Frequency Relevance Heat Pancreatic Cancer 21 99.56 Cancer 9 97.28 Pancreatitis 6 85.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the present study, the expression and functional role of EMMPRIN was investigated in pancreatic neoplasm.

Gene_expression (expression) of EMMPRIN associated with pancreatic cancer

1) Confidence 0.04 Published 2007 Journal Cancer Biol. Ther. Section Abstract Doc Link 17224648 Disease Relevance 0.36 Pain Relevance 0.19

In conclusion, Increased EMMPRIN expression is present in different pancreatic neoplasm, likely representing a tumor-specific reaction with the potential to modulate the tumor microenvironment rather than a mere reflection of an activated stroma.

Gene_expression (expression) of EMMPRIN in stroma associated with cancer and pancreatic cancer

2) Confidence 0.04 Published 2007 Journal Cancer Biol. Ther. Section Abstract Doc Link 17224648 Disease Relevance 0.89 Pain Relevance 0.19

Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells.

Gene_expression (Expression) of EMMPRIN in stellate cells associated with pancreatic cancer and metalloproteinase

3) Confidence 0.04 Published 2007 Journal Cancer Biol. Ther. Section Title Doc Link 17224648 Disease Relevance 0.50 Pain Relevance 0.21

General Comments

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