INT141384

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Faah) Golgi apparatus (Faah) endoplasmic reticulum (Faah)
nucleolus (Urb1) cytoplasm (Faah)
Anatomy Link Frequency
neurons 1
Urb1 (Rattus norvegicus)
Faah (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 2 100.00 Very High Very High Very High
imagery 1 99.22 Very High Very High Very High
Dopamine 4 98.12 Very High Very High Very High
nociceptor 1 97.76 Very High Very High Very High
qutenza 8 97.00 Very High Very High Very High
dorsal root ganglion 5 95.76 Very High Very High Very High
Cannabinoid 1 94.80 High High
Endocannabinoid 1 92.04 High High
antagonist 2 80.72 Quite High
Raphe 1 54.68 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 5 95.76 Very High Very High Very High
Sleep Disorders 1 20.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of the fatty acid amide hydrolase inhibitor URB597 on the sleep-wake cycle, c-Fos expression and dopamine levels of the rat.
URB597 Regulation (Effects) of fatty acid amide hydrolase associated with dopamine and analgesic
1) Confidence 0.08 Published 2007 Journal Eur. J. Pharmacol. Section Title Doc Link 17336288 Disease Relevance 0 Pain Relevance 0.31
Calcium-imaging studies were performed to compare the effects of the fatty acid amide hydrolase (FAAH) inhibitor URB597 (1 microm) vs. the anandamide (AEA) uptake inhibitor UCM707 (1 microm) on capsaicin (100 nm) and N-arachidonoyl dopamine (NADA; 1 microm)-evoked changes in intracellular calcium [Ca(2+)](i) in DRG neurons.
URB597 Regulation (effects) of fatty acid amide hydrolase in neurons associated with dorsal root ganglion, dopamine, qutenza and imagery
2) Confidence 0.01 Published 2006 Journal Eur. J. Neurosci. Section Abstract Doc Link 17229097 Disease Relevance 0.35 Pain Relevance 0.68

General Comments

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