INT141444

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Context Info
Confidence 0.70
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.76
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cav1) mitochondrion (Cav1) Golgi apparatus (Cav1)
endoplasmic reticulum (Cav1) intracellular (Cav1) protein complex (Cav1)
Anatomy Link Frequency
sciatic nerves 4
Cav1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 12 99.68 Very High Very High Very High
Neuritis 16 98.40 Very High Very High Very High
Inflammation 10 79.04 Quite High
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 16 98.40 Very High Very High Very High
Immunization 2 95.88 Very High Very High Very High
INFLAMMATION 10 79.04 Quite High
Apoptosis 2 58.88 Quite High
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased phosphorylation of caveolin-1 in the sciatic nerves of Lewis rats with experimental autoimmune neuritis.
Positive_regulation (Increased) of Phosphorylation (phosphorylation) of caveolin-1 in sciatic nerves associated with experimental autoimmune neuritis, sciatic nerve and neuritis
1) Confidence 0.70 Published 2007 Journal Brain Res. Section Title Doc Link 17234162 Disease Relevance 0.93 Pain Relevance 0.86
Western blot analysis showed that the phosphorylation of caveolin-1 increased significantly in the sciatic nerves of EAN-affected rats at the paralytic stage of EAN on day 14 post-immunization (PI) (P<0.05) and declined slightly thereafter during the recovery stage.
Positive_regulation (increased) of Phosphorylation (phosphorylation) of caveolin-1 in sciatic nerves associated with immunization, sciatic nerve and neuritis
2) Confidence 0.70 Published 2007 Journal Brain Res. Section Abstract Doc Link 17234162 Disease Relevance 0.83 Pain Relevance 0.83

General Comments

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