INT141455

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.09
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Inpp5k) endoplasmic reticulum (Inpp5k) plasma membrane (Inpp5k)
nucleus (Inpp5k) cytoplasm (Inpp5k)
Anatomy Link Frequency
tail 1
Inpp5k (Mus musculus)
Pain Link Frequency Relevance Heat
antinociception 3 98.04 Very High Very High Very High
Morphine 15 96.96 Very High Very High Very High
tail-flick 1 94.56 High High
Antinociceptive 3 91.72 High High
analgesia 1 51.84 Quite High
Pain 10 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatigue 49 100.00 Very High Very High Very High
Postpoliomyelitis Syndrome 47 100.00 Very High Very High Very High
Chronic Fatigue Syndrome 2 92.72 High High
Cancer 2 89.68 High High
Cognitive Disorder 11 50.00 Quite Low
Polio 15 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Muscle Weakness 3 5.00 Very Low Very Low Very Low
Neuromuscular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We evaluated the effects of both okadaic acid (a selective inhibitor of some serine/threonine PPs) and its inactive analogue L-norokadaone on the antinociception induced by morphine in morphine-naive and -tolerant female mice in the tail-flick test.
Negative_regulation (inhibitor) of PPs in tail associated with antinociception, tail-flick and morphine
1) Confidence 0.36 Published 2007 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 17234262 Disease Relevance 0 Pain Relevance 1.51
This is the first study that will evaluate the efficacy of CBT in reducing fatigue in PPS.
Negative_regulation (reducing) of PPS associated with fatigue and postpoliomyelitis syndrome
2) Confidence 0.31 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2821386 Disease Relevance 1.09 Pain Relevance 0

General Comments

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