INT141529

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2008
Negated 3
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.31
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (APP) extracellular matrix organization (APP) DNA binding (APP)
cytoplasm (APP) cytosol (APP) extracellular region (APP)
APP (Homo sapiens)
Pain Link Frequency Relevance Heat
Abeta 22 100.00 Very High Very High Very High
cINOD 7 97.94 Very High Very High Very High
agonist 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 97.66 Very High Very High Very High
Alzheimer's Dementia 9 56.64 Quite High
Disease 9 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, OSBP1 overexpression was unable to further alter the concomitant increase in APP-CTF?
Neg (unable) Regulation (alter) of Positive_regulation (increase) of APP
1) Confidence 0.44 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2323375 Disease Relevance 0 Pain Relevance 0
In addition, the non-steroidal anti-inflammatory drugs (NSAIDs) ibuprofen and sulindac sulfide have no effect on the formation and turnover of Abeta(46), but rather modulate the ratio of secreted Abeta at a step after the formation of Abeta(40) and Abeta(42).
Neg (no) Regulation (modulate) of Positive_regulation (formation) of Abeta associated with inflammation, cinod and abeta
2) Confidence 0.09 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17241131 Disease Relevance 0.15 Pain Relevance 0.67
In addition, the non-steroidal anti-inflammatory drugs (NSAIDs) ibuprofen and sulindac sulfide have no effect on the formation and turnover of Abeta(46), but rather modulate the ratio of secreted Abeta at a step after the formation of Abeta(40) and Abeta(42).
Neg (no) Regulation (modulate) of Positive_regulation (formation) of Abeta associated with inflammation, cinod and abeta
3) Confidence 0.09 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17241131 Disease Relevance 0.15 Pain Relevance 0.67

General Comments

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