INT141545

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.45 Pain Relevance 0.27

endoplasmic reticulum (Bace1, Rtn4) endosome (Bace1) nuclear envelope (Rtn4) peptidase activity (Bace1) Golgi apparatus (Bace1) plasma membrane (Rtn4)

Bace1 (Rattus norvegicus) Rtn4 (Mus musculus)

Pain Link Frequency Relevance Heat Abeta 5 88.24 cINOD 1 77.44

Disease Link Frequency Relevance Heat Disease 2 83.40 Disorder Of Lipid Metabolism 1 79.68 INFLAMMATION 1 77.04 Alzheimer's Dementia 3 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Mints and NgR bind to APP directly, while RTN3 and Nogo-B interact with the beta-secretase BACE1.

beta-secretase BACE1 Binding (interact) of Nogo-B

1) Confidence 0.00 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17241154 Disease Relevance 0.45 Pain Relevance 0.27

General Comments

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