INT141591

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GPT) small molecule metabolic process (GPT) biosynthetic process (GPT)
cellular nitrogen compound metabolic process (GPT) cytoplasm (GPT)
Anatomy Link Frequency
blood 2
GPT (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 5 97.88 Very High Very High Very High
anesthesia 5 92.88 High High
epidural 2 88.56 High High
isoflurane 1 85.36 High High
Bile 17 53.32 Quite High
agonist 1 38.84 Quite Low
imagery 90 8.20 Low Low
fibrosis 7 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 1 98.08 Very High Very High Very High
Pain 5 97.88 Very High Very High Very High
Vomiting 5 97.50 Very High Very High Very High
Pressure Volume 2 Under Development 1 97.20 Very High Very High Very High
Cirrhosis 13 96.64 Very High Very High Very High
Coagulation Disorder 2 74.32 Quite High
Renal Failure 2 60.64 Quite High
Necrosis 3 46.76 Quite Low
Hypersensitivity 7 40.08 Quite Low
Asthma 2 33.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preoperative serum examination revealed increases in GOT, GPT, LDH and total bilirubin, decreases in cholinesterase and albumin, and prolongation of prothrombin time.
Negative_regulation (decreases) of Positive_regulation (increases) of GPT
1) Confidence 0.42 Published 2007 Journal Masui Section Abstract Doc Link 17243650 Disease Relevance 0.38 Pain Relevance 0.68
Other AEs were reported in 20 of 234 patients, including nausea (2 patients), pain at the injection site (1), increased systolic/diastolic blood pressure (2), increased blood glucose (2), decreased white blood cell count (2), increased blood bilirubin (3), increased blood phosphorus (1), increased alanine aminotransferase (1), increased aspartate aminotransferase (1), hypertension (4), and hypotension (2).46

Effect of hepatic and renal impairment

Negative_regulation (decreased) of Positive_regulation (increased) of alanine aminotransferase in blood associated with pain, pressure volume 2 under development, hypertension and vomiting
2) Confidence 0.42 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2921257 Disease Relevance 0.45 Pain Relevance 0.12

General Comments

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