INT14177

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Context Info
Confidence 0.05
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.71

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small molecule metabolic process (DHCR24) Golgi apparatus (DHCR24) endoplasmic reticulum (DHCR24)
enzyme binding (DHCR24) cytoplasm (DHCR24) cytosol (DHCR24)
DHCR24 (Homo sapiens)
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 12 100.00 Very High Very High Very High
Enkephalin 2 99.36 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This enzyme (hCSF-DCE) cleaves dynorphin A, dynorphin B and alpha-neoendorphin to release Leu-enkephalin-Arg6.
hCSF-DCE Positive_regulation (cleaves) of alpha-neoendorphin associated with dynorphin and enkephalin
1) Confidence 0.05 Published 1991 Journal J. Enzym. Inhib. Section Abstract Doc Link 1688305 Disease Relevance 0 Pain Relevance 0.35
This enzyme (hCSF-DCE) cleaves dynorphin A, dynorphin B and alpha-neoendorphin to release Leu-enkephalin-Arg6.
hCSF-DCE Positive_regulation (cleaves) of dynorphin B associated with dynorphin and enkephalin
2) Confidence 0.05 Published 1991 Journal J. Enzym. Inhib. Section Abstract Doc Link 1688305 Disease Relevance 0 Pain Relevance 0.35

General Comments

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