INT141907

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Context Info
Confidence 0.46
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Plat) extracellular space (Plat) signal transduction (F2r)
extracellular region (Plat) plasma membrane (F2r) cytoplasm (Plat)
Anatomy Link Frequency
NAc 1
F2r (Mus musculus)
Plat (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 9 98.60 Very High Very High Very High
Dopamine 8 97.92 Very High Very High Very High
Antinociceptive 1 97.72 Very High Very High Very High
Nucleus accumbens 7 96.96 Very High Very High Very High
antagonist 3 96.24 Very High Very High Very High
Intracerebroventricular 1 94.88 High High
Eae 1 86.88 High High
narcan 2 75.40 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that PAR-1 is a target for the tPA-plasmin system in the regulation of acute morphine-induced dopamine release in the NAc.
PAR-1 Regulation (target) of tPA-plasmin in NAc associated with nucleus accumbens, dopamine and morphine
1) Confidence 0.46 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17286591 Disease Relevance 0 Pain Relevance 1.59

General Comments

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