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Context Info
Confidence 0.19
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.31
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gnaq) signal transduction (Gnaq) plasma membrane (Gnaq)
GTPase activity (Gnaq) protein complex (Gnaq) signal transducer activity (Gnaq)
Gnaq (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 94.04 High High
fluoxetine 4 92.28 High High
b2 receptor 1 91.28 High High
depression 3 83.72 Quite High
bradykinin 10 83.12 Quite High
agonist 81 82.88 Quite High
Serotonin 10 75.00 Quite High
Catecholamine 3 17.40 Low Low
antagonist 9 6.68 Low Low
Kinase C 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 12 99.40 Very High Very High Very High
Asthma 43 95.08 Very High Very High Very High
Common Cold 1 94.52 High High
Depression 3 83.72 Quite High
Occupational Lung Diseases 9 67.52 Quite High
Anxiety Disorder 1 53.92 Quite High
Sprains And Strains 1 52.48 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Enriched and nonenriched BALB/c mice exposed to early life stress also exhibited significantly increased expression of mRNA and protein encoding the G alpha q subunit of G-protein that couples to 5-HT2A/2C receptors.
Positive_regulation (increased) of Gene_expression (expression) of alpha q associated with stress
1) Confidence 0.19 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17287521 Disease Relevance 1.05 Pain Relevance 0.49
Therefore, we could use drugs with distinct chemical structures (Figure S1) to activate Gs or Gs/Gq signaling of Rs1.
Positive_regulation (activate) of Gene_expression (signaling) of Gq
2) Confidence 0.05 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2267039 Disease Relevance 0 Pain Relevance 0.04
[180], has been shown to increase expression of either Gq or specific G?
Positive_regulation (increase) of Gene_expression (expression) of Gq
3) Confidence 0.05 Published 2003 Journal Respir Res Section Body Doc Link PMC152647 Disease Relevance 0.26 Pain Relevance 0.23

General Comments

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