INT142079

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (AIF1) plasma membrane (AIF1) cytoskeleton (AIF1)
nucleus (AIF1) response to stress (AIF1) cytoplasm (AIF1)
AIF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
cytokine 5 95.52 Very High Very High Very High
headache 9 75.00 Quite High
cva 2 58.24 Quite High
Central nervous system 6 44.68 Quite Low
Migraine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 100.00 Very High Very High Very High
Headache 10 75.00 Quite High
Cerebral Toxoplasmosis 2 75.00 Quite High
Immunodeficiency 2 75.00 Quite High
Neurogenic Inflammation 1 75.00 Quite High
Lymphadenopathy 1 75.00 Quite High
Pseudotumor Cerebri 2 59.12 Quite High
Infection 5 56.80 Quite High
Viral Meningitis 1 54.08 Quite High
Urinary Tract Disease 1 34.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, NO inhibits IDO activity, thereby suppressing kynurenine formation, and at least one member of the kynurenine pathway, 3-hydroxyanthranilic acid, has been shown to inhibit NOS enzyme activity, the expression of NOS mRNA, and activation of the inflammatory transcription factor, nuclear factor-kB.
Negative_regulation (inhibit) of Positive_regulation (activation) of inflammatory transcription factor associated with inflammation
1) Confidence 0.00 Published 2007 Journal Am J Ther Section Abstract Doc Link 17303977 Disease Relevance 1.01 Pain Relevance 0.57

General Comments

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