INT142084

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Context Info
Confidence 0.29
First Reported 2006
Last Reported 2010
Negated 4
Speculated 0
Reported most in Body
Documents 22
Total Number 22
Disease Relevance 5.88
Pain Relevance 3.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Kdm5d) nucleus (Kdm5d) intracellular (Kdm5d)
DNA binding (Kdm5d)
Anatomy Link Frequency
superior 1
Kdm5d (Mus musculus)
Pain Link Frequency Relevance Heat
visual analogue scale 46 99.96 Very High Very High Very High
rheumatoid arthritis 137 99.40 Very High Very High Very High
Arthritis 83 95.36 Very High Very High Very High
Angina 59 94.12 High High
cva 19 93.12 High High
Infliximab 10 93.04 High High
pregabalin 7 91.48 High High
Inflammation 49 91.36 High High
Osteoarthritis 2 90.56 High High
Pain 86 90.24 High High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 138 99.40 Very High Very High Very High
Disease 410 99.04 Very High Very High Very High
Nicotine Addiction 5 98.56 Very High Very High Very High
Cancer 9 96.96 Very High Very High Very High
Arthritis 82 95.36 Very High Very High Very High
Angina 38 94.12 High High
Cv General 3 Under Development 40 93.12 High High
Myocardial Infarction 34 92.56 High High
INFLAMMATION 18 91.36 High High
Coronary Artery Disease 47 90.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gain in EQ-5D for individuals in residential care was 0.0582 units bigger than that of individuals in non-residential care while a 1 unit increase in the ratio of support staff to qualified staff increased the change in EQ-5D by 0.0464 units.
Positive_regulation (increased) of EQ-5D
1) Confidence 0.29 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2921080 Disease Relevance 0 Pain Relevance 0
Initially, studies that reported EQ-5D index-based scores and/or VAS scores were sorted into cardiovascular subgroups (e.g.
Positive_regulation (reported) of EQ-5D associated with visual analogue scale
2) Confidence 0.24 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2824714 Disease Relevance 0.66 Pain Relevance 0.16
There is strong evidence that lower EQ-5D scores on admission are associated with greater improvements in EQ-5D over the period of care (Table 2).
Positive_regulation (improvements) of EQ-5D
3) Confidence 0.21 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2921080 Disease Relevance 0 Pain Relevance 0
However, using the model to predict the observed EQ-5D index in the validation dataset did not indicate good prediction on average and the Bland-Altman plot showed that the mapping model over-estimated the EQ-5D index for people with observed values of approximately 0.4 and below in both the estimation and validation datasets.
Positive_regulation (estimated) of EQ-5D
4) Confidence 0.19 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2900231 Disease Relevance 0.07 Pain Relevance 0.07
Including the EQ-5D response levels considerably increased the model fit (R2 = 0.31) on the one hand, while independent variables age and income became insignificant on the other.
Positive_regulation (increased) of EQ-5D
5) Confidence 0.06 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC3009699 Disease Relevance 0.42 Pain Relevance 0.24
While at admission, the worst state did not occur for the EQ-5D and the SF-12, it was observed for the SGRQ subscores symptoms and activity in 5% and 11% of patients, respectively.
Neg (not) Positive_regulation (occur) of EQ-5D
6) Confidence 0.05 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2864208 Disease Relevance 0.26 Pain Relevance 0
In Germany and South Africa, VAS scores were counted as missing when the standard adult EQ-5D VAS was not filled out correctly i.e. when respondents did something other than drawing a line from the box with the words ‘your health today’ to their chosen VAS score.
Positive_regulation (adult) of EQ-5D
7) Confidence 0.04 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2892611 Disease Relevance 0.13 Pain Relevance 0
However, NICE recognises that the EQ-5D is not always collected, and in these circumstances suggests that methods may be used to estimate EQ-5D utility values by mapping.
Positive_regulation (estimate) of EQ-5D
8) Confidence 0.03 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2829532 Disease Relevance 0.20 Pain Relevance 0.05
The students reported a mean EQ-5D VAS score of 87.3 (± 9.6) with no significant differences between male and female students (male: 87.1 ± 7.8; female: 87.9 ± 10.0, t-Test: p > .05).
Positive_regulation (mean) of EQ-5D associated with visual analogue scale
9) Confidence 0.03 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2636775 Disease Relevance 0.10 Pain Relevance 0.15
-based cancer patients self-assessed their health using EQ-5D-3L and EQ-5D-5L.
Positive_regulation (using) of EQ-5D
10) Confidence 0.03 Published 2007 Journal Med Care Section Body Doc Link 17304084 Disease Relevance 0.10 Pain Relevance 0
-based cancer patients self-assessed their health using EQ-5D-3L and EQ-5D-5L.
Positive_regulation (using) of EQ-5D
11) Confidence 0.03 Published 2007 Journal Med Care Section Body Doc Link 17304084 Disease Relevance 0.10 Pain Relevance 0
The SF-6D has smaller increments between scoring levels than the EQ-5D which allows patients to report smaller improvements.
Positive_regulation (increments) of EQ-5D
12) Confidence 0.03 Published 2009 Journal Qual Life Res Section Body Doc Link PMC2761817 Disease Relevance 0.14 Pain Relevance 0
Only half of the STIVEA patients will have been randomised to steroid treatment as part of the trial.moderate to large improvements in EQ-5D and SF-6D (ES > 0.5) in BRSBR patients.
Positive_regulation (improvements) of EQ-5D
13) Confidence 0.03 Published 2009 Journal Qual Life Res Section Body Doc Link PMC2761817 Disease Relevance 0.55 Pain Relevance 0.30
This suggests that the superior responsiveness of the EQ-5D to deterioration in health in this group is related to some aspect other than functional disability or disease activity.
Positive_regulation (responsiveness) of EQ-5D in superior associated with disease
14) Confidence 0.03 Published 2009 Journal Qual Life Res Section Body Doc Link PMC2761817 Disease Relevance 0.39 Pain Relevance 0.11
The ES for patients from patients reporting a deterioration over 1 year of follow-up (BROSG(D) was larger than anticipated for both the EQ-5D (ES = 0.62) and SF-6D (ES = 0.35).
Positive_regulation (anticipated) of EQ-5D
15) Confidence 0.03 Published 2009 Journal Qual Life Res Section Body Doc Link PMC2761817 Disease Relevance 0 Pain Relevance 0
However, the change in EQ-5D for this latter group of patients was in excess of estimates of the minimum important difference for this measure [8].
Positive_regulation (change) of EQ-5D
16) Confidence 0.03 Published 2009 Journal Qual Life Res Section Body Doc Link PMC2761817 Disease Relevance 0.17 Pain Relevance 0.05
A national effort in designing a study with a representative sample of the Italian population will be a necessary step to increase evidence on the EQ-5D applicability in Italy.


Positive_regulation (increase) of EQ-5D
17) Confidence 0.03 Published 2006 Journal Health Qual Life Outcomes Section Body Doc Link PMC1562359 Disease Relevance 0 Pain Relevance 0
Health state (EQ-5D) increased by 31.6 +/- 22.2 mm (ES 1.67; P < 0.0001), with 0.0388 +/- 0.0374 gained quality-adjusted life-years.
Positive_regulation (increased) of EQ-5D
18) Confidence 0.02 Published 2009 Journal Cephalalgia Section Abstract Doc Link 19522052 Disease Relevance 0.57 Pain Relevance 1.19
By contrast, HRQL did not change: EQ-5D: 0.76 (CI 0.73–0.79) -0.78 (CI 0.75–0.81), EQ-VAS: 0.68 (CI 0.66–0.71)-0.68 (CI 0.65–0.71) and CHP: 0.66 (CI 0.64–0.69) -0.66 (CI 0.64–0.69).


Neg (not) Positive_regulation (change) of EQ-5D
19) Confidence 0.01 Published 2007 Journal Health Qual Life Outcomes Section Abstract Doc Link PMC1821316 Disease Relevance 0.87 Pain Relevance 0.57
Based on blinded data, mean PRO measures improved during the course of the trial (a decrease in DLQI scores indicates an improvement; an increase in the SF-36 and EQ-5D indicates improvement).
Positive_regulation (increase) of EQ-5D
20) Confidence 0.01 Published 2006 Journal Health Qual Life Outcomes Section Body Doc Link PMC1615869 Disease Relevance 0.21 Pain Relevance 0.30

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