INT142119

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Context Info
Confidence 0.58
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Bmp4) anatomical structure formation involved in morphogenesis (Bmp4) extracellular space (Bmp4)
growth (Bmp4) extracellular region (Bmp4) proteinaceous extracellular matrix (Bmp4)
Anatomy Link Frequency
TMJ 1
Bmp4 (Mus musculus)
Pain Link Frequency Relevance Heat
Snapping jaw 5 50.00 Quite Low
methotrexate 17 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mucositis 14 75.00 Quite High
Apoptosis 10 74.16 Quite High
Temporomandibular Joint Syndrome 5 72.88 Quite High
Frailty 7 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 1 5.00 Very Low Very Low Very Low
Solid Tumor 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Temporomandibular Joint Disorders 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: Estrogen plays important roles in the metabolism and maintenance of TMJ via regulations of signaling molecules such as BMP-4, Runx2, and BSP.
Regulation (regulations) of BMP-4 in TMJ
1) Confidence 0.58 Published 2007 Journal Oral Dis Section Body Doc Link 17305626 Disease Relevance 0.07 Pain Relevance 0
These data suggest that in response to DOX-induced damage, BMP4 and TCF4 are modulated in such a way that homeostasis of the progenitor compartment is partly preserved.



Regulation (modulated) of BMP4
2) Confidence 0.26 Published 2007 Journal Dig Dis Sci Section Abstract Doc Link PMC1914222 Disease Relevance 0.22 Pain Relevance 0

General Comments

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