INT142122

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2007
Last Reported 2011
Negated 2
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.69
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Bmp4) anatomical structure formation involved in morphogenesis (Bmp4) extracellular space (Bmp4)
growth (Bmp4) extracellular region (Bmp4) proteinaceous extracellular matrix (Bmp4)
Anatomy Link Frequency
cartilage 2
temporomandibular joint 2
Bmp4 (Mus musculus)
Pain Link Frequency Relevance Heat
Snapping jaw 5 99.24 Very High Very High Very High
antagonist 8 98.36 Very High Very High Very High
Central nervous system 22 91.04 High High
methotrexate 34 82.96 Quite High
cytokine 14 82.40 Quite High
Inflammation 81 82.00 Quite High
cINOD 28 80.32 Quite High
Inflammatory response 10 56.64 Quite High
fibrosis 1 47.36 Quite Low
Hippocampus 35 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 99.88 Very High Very High Very High
Temporomandibular Joint Syndrome 5 99.24 Very High Very High Very High
Temporomandibular Joint Disorders 1 97.52 Very High Very High Very High
Respiratory Failure 1 96.96 Very High Very High Very High
Congenital Anomalies 6 91.76 High High
Heterotopic Ossification 87 88.08 High High
Neurodegenerative Disease 128 86.24 High High
INFLAMMATION 95 82.00 Quite High
Gliosis 23 78.28 Quite High
Atherosclerosis 1 73.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thereafter, BMP4 day 2 but not to control.
Neg (not) Regulation (control) of Gene_expression (day) of BMP4
1) Confidence 0.43 Published 2007 Journal Dig Dis Sci Section Body Doc Link PMC1914222 Disease Relevance 0.09 Pain Relevance 0.04
Alteration of BMP-4 and Runx2 expression patterns in mouse temporomandibular joint after ovariectomy.
Regulation (Alteration) of Gene_expression (expression) of BMP-4 in temporomandibular joint associated with snapping jaw
2) Confidence 0.26 Published 2007 Journal Oral Dis Section Title Doc Link 17305626 Disease Relevance 0.47 Pain Relevance 0.45
The localization of BMP4 expression did not change at day three (C) in comparison to control situation (B).
Neg (not) Regulation (change) of Gene_expression (expression) of BMP4
3) Confidence 0.26 Published 2007 Journal Dig Dis Sci Section Body Doc Link PMC1914222 Disease Relevance 0.12 Pain Relevance 0.04
superfamily molecules, especially BMP4, BMP7, and TGF?
Regulation (especially) of Gene_expression (molecules) of BMP4
4) Confidence 0.17 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0.94 Pain Relevance 0.32
Transgenic mice expressing BMP4 in cartilage under the control of the Col11a2 promoter/enhancer sequences die at birth due to respiratory failure [58] while mice overexpressing human BMP4 under control of mouse Msx1 minimal promoter develop no visible abnormalities [33].
Regulation (under) of Gene_expression (expressing) of BMP4 in cartilage associated with targeted disruption, congenital anomalies and respiratory failure
5) Confidence 0.13 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2963134 Disease Relevance 1.08 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox