INT142147

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.58
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il5) extracellular region (Il5)
Anatomy Link Frequency
lung 2
Il5 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 10 97.28 Very High Very High Very High
cytokine 67 96.32 Very High Very High Very High
Inflammation 40 95.92 Very High Very High Very High
antagonist 41 91.20 High High
withdrawal 2 17.92 Low Low
dexamethasone 13 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Endogenous opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 4 98.52 Very High Very High Very High
Cancer 14 98.16 Very High Very High Very High
Asthma 43 96.84 Very High Very High Very High
Infection 78 96.24 Very High Very High Very High
INFLAMMATION 36 95.92 Very High Very High Very High
Parasitemia 6 88.92 High High
Disease 8 87.92 High High
Pneumonia 4 87.40 High High
Atrophy 9 77.84 Quite High
Death 25 60.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oral administration of 3 mg/kg/day capsaicin, one active constituent of the extract, also enhanced IL-2, INF-gamma and IL-4 production in response to Con A stimulation but did not influence the production of IL-5.
Neg (not) Regulation (influence) of Gene_expression (production) of IL-5 associated with qutenza
1) Confidence 0.22 Published 2007 Journal Life Sci. Section Abstract Doc Link 17306834 Disease Relevance 0 Pain Relevance 0.54
Nevertheless our data is consistent with previous reports showing that over expression of IL-13 did not alter IL-5 expression in mouse lung [9], nor was it affected by IL-13 genetic deficiency in a mouse asthma model [20].
Neg (not) Regulation (alter) of Gene_expression (expression) of IL-5 in lung associated with asthma
2) Confidence 0.11 Published 2010 Journal Respir Res Section Body Doc Link PMC2914735 Disease Relevance 0.34 Pain Relevance 0.23
, with no significant differences in IL-4 and IL-5 production [41].
Neg (no) Regulation (differences) of Gene_expression (production) of IL-5
3) Confidence 0.06 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2700264 Disease Relevance 1.01 Pain Relevance 0.12
In contrast, no expression of IL-2 and IL-5 could be found.
Regulation (found) of Gene_expression (expression) of IL-5
4) Confidence 0.03 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1062151 Disease Relevance 0.23 Pain Relevance 0.18

General Comments

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