INT142156

Context Info Confidence 0.06 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0.75

mitochondrion (Polg) aging (Polg)

Anatomy Link Frequency B16-F10 1 Polg (Mus musculus)

Pain Link Frequency Relevance Heat qutenza 10 98.48

Disease Link Frequency Relevance Heat Skin Cancer 3 83.60 Apoptosis 3 81.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Treatment of B16-F10 cells with capsaicin caused release of mitochondrial cytochrome c, activation of caspase-3, and cleavage of poly (ADP-ribose) polymerase in a dose-dependent manner.

Protein_catabolism (cleavage) of polymerase in B16-F10 associated with qutenza

1) Confidence 0.06 Published 2007 Journal Food Chem. Toxicol. Section Abstract Doc Link 17306913 Disease Relevance 0.32 Pain Relevance 0.75

General Comments

This test has worked.