INT142226

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Context Info
Confidence 0.35
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) plasma membrane (Trpv1) lipid metabolic process (Trpv1)
transmembrane transport (Trpa1)
Trpa1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Root ganglion neuron 1 97.68 Very High Very High Very High
agonist 15 95.84 Very High Very High Very High
Thermal hyperalgesia 1 95.00 High High
vincristine 1 85.12 High High
qutenza 29 81.92 Quite High
Antinociceptive 1 76.56 Quite High
Lasting pain 4 51.56 Quite High
Pain 5 45.20 Quite Low
imagery 4 43.36 Quite Low
Paresthesia 1 30.68 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 97.36 Very High Very High Very High
Hyperalgesia 3 95.00 High High
Neuropathic Pain 7 83.20 Quite High
Toxicity 4 59.68 Quite High
Pain 8 51.56 Quite High
Nociception 1 44.48 Quite Low
Death 1 35.72 Quite Low
Dysesthesia 1 30.00 Quite Low
Congenital Anomalies 1 21.52 Low Low
Hypersensitivity 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional effects of oxaliplatin treatment on TRPV1, TRPA1/M8
TRPA1/M8 Regulation (effects) of TRPV1
1) Confidence 0.35 Published 2010 Journal Mol Pain Section Body Doc Link PMC3003244 Disease Relevance 0.29 Pain Relevance 0.27
In contrast to its effect on TRPA1, URB597 inhibited TRPM8 and had no effects on TRPV1 or TRPV4.
TRPA1 Neg (no) Regulation (effects) of TRPV1
2) Confidence 0.14 Published 2007 Journal Mol. Pharmacol. Section Abstract Doc Link 17314320 Disease Relevance 0.10 Pain Relevance 0.17

General Comments

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