INT142244

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Context Info
Confidence 0.77
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk2) cytosol (Ntrk2) plasma membrane (Ntrk2)
kinase activity (Ntrk2)
Anatomy Link Frequency
neuronal 2
Ntrk2 (Mus musculus)
Tcrg-C1 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 12 99.76 Very High Very High Very High
Hippocampus 1 96.52 Very High Very High Very High
Anterior cingulate cortex 1 95.88 Very High Very High Very High
monoamine 2 92.24 High High
fluoxetine 1 80.60 Quite High
Eae 1 72.08 Quite High
Serotonin 1 40.16 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the results indicate that acute and long-term antidepressant treatments induce TrkB-mediated activation of phospholipase-Cgamma1 (PLCgamma1) and increase the phosphorylation of cAMP-related element binding protein, a major transcription factor mediating neuronal plasticity.
Positive_regulation (induce) of TrkB Positive_regulation (activation) of Cgamma1 in neuronal associated with antidepressant
1) Confidence 0.77 Published 2007 Journal Neuropsychopharmacology Section Abstract Doc Link 17314919 Disease Relevance 0 Pain Relevance 0.67

General Comments

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