INT142309

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.34
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Accn3) cytoplasm (Accn3)
Anatomy Link Frequency
DRGs 2
Accn3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hyperalgesia 5 98.68 Very High Very High Very High
nociceptor 3 94.48 High High
TRP channel 1 92.92 High High
ASIC 4 91.24 High High
c fibre 4 90.88 High High
Pain 12 88.16 High High
Spinal cord 8 83.84 Quite High
Inflammation 8 75.28 Quite High
Cancer pain 1 60.20 Quite High
unmyelinated 1 44.12 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 7 99.72 Very High Very High Very High
Targeted Disruption 4 99.24 Very High Very High Very High
Hyperalgesia 5 98.68 Very High Very High Very High
Acidosis 2 87.96 High High
Cancer 3 76.08 Quite High
INFLAMMATION 7 75.28 Quite High
Pain 6 75.00 Quite High
Breast Cancer 1 64.96 Quite High
Cancer Pain 1 60.20 Quite High
Hypercalcemia 1 46.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of ASIC1a and ASIC1b was increased in the ipsilateral DRGs, whereas the ASIC3 and TRPV1 expression was not changed.
Neg (not) Regulation (changed) of Gene_expression (expression) of ASIC3 in DRGs associated with ganglion cysts
1) Confidence 0.50 Published 2007 Journal J. Bone Miner. Metab. Section Abstract Doc Link 17323179 Disease Relevance 1.06 Pain Relevance 0.67
-fibres which is dependent on the expression of ASIC3 as shown in ASIC3 knockout mice [25].
Regulation (dependent) of Gene_expression (expression) of ASIC3 associated with targeted disruption
2) Confidence 0.39 Published 2006 Journal Respir Res Section Body Doc Link PMC1524950 Disease Relevance 0.27 Pain Relevance 0.49

General Comments

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