INT142384

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Context Info
Confidence 0.58
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.98
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (XRCC6) lyase activity (XRCC6) chromosome (XRCC6)
nucleus (XRCC6) helicase activity (XRCC6) DNA binding (XRCC6)
Anatomy Link Frequency
PSP 1
XRCC6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 8 79.88 Quite High
carpal tunnel syndrome 1 58.64 Quite High
Spinal cord 8 51.00 Quite High
Multiple sclerosis 21 40.04 Quite Low
Inflammation 13 32.64 Quite Low
Central nervous system 12 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myositis 1 100.00 Very High Very High Very High
Syndrome 2 99.12 Very High Very High Very High
Stress 1 97.04 Very High Very High Very High
Bullous Skin Disease 1 94.76 High High
Cancer 9 86.64 High High
Temporomandibular Joint Syndrome 1 86.28 High High
Neuromyelitis Optica 78 84.00 Quite High
Myeloid Leukemia 25 83.28 Quite High
Optic Disorders 2 80.56 Quite High
Optic Neuritis 8 79.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The film and the PSP plate tomograms were exposed in a Cranex Tome X-ray unit and the CCD tomograms in the ProMax X-ray unit.
Gene_expression (exposed) of X-ray unit in PSP
1) Confidence 0.58 Published 2007 Journal Dentomaxillofac Radiol Section Body Doc Link 17329582 Disease Relevance 0.09 Pain Relevance 0
In imatinib-resistant K562 cell line, the expression of cytoplasmic Ku70 is increased, while the amount of acetylated Ku70 is markedly decreased, suggesting that Bax-mediated apopotosis is inhibited [12].
Gene_expression (expression) of Ku70
2) Confidence 0.12 Published 2010 Journal Invest New Drugs Section Body Doc Link PMC3003795 Disease Relevance 0.53 Pain Relevance 0
Addison- and autoimmune polyendocrine syndrome-associated steroid 21-hydroxylase; and the myositis-associated autoantigen Ku 80, expressed in the same vector system (unpublished data).


Gene_expression (expressed) of myositis-associated autoantigen Ku 80 associated with syndrome and myositis
3) Confidence 0.05 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1852124 Disease Relevance 1.37 Pain Relevance 0.16

General Comments

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