INT142420

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) oxidoreductase activity (Nqo1) aging (Nqo1)
cytoplasm (Nqo1)
Anatomy Link Frequency
liver 2
spine 2
Nqo1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 2 91.20 High High
Central grey 1 71.92 Quite High
Dorsal horn 1 63.48 Quite High
Pain 1 42.12 Quite Low
qutenza 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Muscle Weakness 1 97.60 Very High Very High Very High
Fatigue 2 88.16 High High
Urological Neuroanatomy 1 71.92 Quite High
Nociception 1 5.00 Very Low Very Low Very Low
Myalgia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Investigation of c-fos expression and NADPH-diaphorase activity in the spine cord and brain in the development of the neck muscle weakness in rats].
Negative_regulation ([Investigation) of Gene_expression (activity) of NADPH-diaphorase in spine associated with muscle weakness
1) Confidence 0.41 Published 2006 Journal Fiziol Zh Section Title Doc Link 17333617 Disease Relevance 0.26 Pain Relevance 0.15
We purified an NADPH-dependent coenzyme Q reductase (NADPH-CoQ reductase) in rat liver cytosol and compared its enzymatic properties with those of the other CoQ10 reductases such as NADPH: quinone acceptor oxidoreductase 1 (NQO1), lipoamide dehydrogenase, thioredoxine reductase and glutathione reductase.
Negative_regulation (thioredoxine reductase) of Gene_expression (reductases) of NQO1 in liver
2) Confidence 0.40 Published 2008 Journal Biofactors Section Abstract Doc Link 19096101 Disease Relevance 0 Pain Relevance 0

General Comments

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