INT14257

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Context Info
Confidence 0.73
First Reported 1980
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 1.48
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TSPO) mitochondrion (TSPO) aging (TSPO)
response to stress (TSPO)
Anatomy Link Frequency
tear 2
puncture 1
brain 1
small intestine 1
TSPO (Homo sapiens)
Pain Link Frequency Relevance Heat
Versed 5 100.00 Very High Very High Very High
agonist 2 100.00 Very High Very High Very High
cINOD 20 99.48 Very High Very High Very High
Acupuncture 62 97.70 Very High Very High Very High
positron emission tomography 1 97.60 Very High Very High Very High
Neurotransmitter 3 97.20 Very High Very High Very High
diclofenac 80 96.96 Very High Very High Very High
antagonist 2 91.92 High High
tramadol 21 87.96 High High
Substantia nigra 13 86.88 High High
Disease Link Frequency Relevance Heat
Disease 28 99.92 Very High Very High Very High
INFLAMMATION 37 99.24 Very High Very High Very High
Pulmonary Disease 5 96.62 Very High Very High Very High
Parkinson's Disease 8 94.64 High High
Cancer 4 82.72 Quite High
Necrosis 3 82.24 Quite High
Respiratory Disease 11 80.96 Quite High
Apoptosis 44 50.00 Quite Low
Neuroblastoma 10 50.00 Quite Low
Nerve Degeneration 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PBS: phosphate buffered saline
Localization (saline) of PBS
1) Confidence 0.73 Published 2004 Journal J Neuroinflammation Section Body Doc Link PMC483059 Disease Relevance 0.92 Pain Relevance 0.56
The benzodiazepine receptor agonist, midazolam, concentration-dependently increased (by 58%, at 1 nmol/l) and decreased (by 32%, at 100 nmol/l) the release of 5-HT from small intestine preparations.
Localization (release) of benzodiazepine receptor in small intestine associated with versed and agonist
2) Confidence 0.63 Published 1990 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 1690357 Disease Relevance 0 Pain Relevance 0.58
There exists a saturable, high-affinity, stereospecific, regionally and pharmacologically specific, neuronally localized benzodiazepine receptor in mammalian brain, which has a development profile similar to other neurotransmitter receptors.
Localization (localized) of benzodiazepine receptor in brain associated with neurotransmitter
3) Confidence 0.63 Published 1980 Journal Fed. Proc. Section Abstract Doc Link 6998742 Disease Relevance 0 Pain Relevance 0.07
Chronic obstructive pulmonary diseases (COPD), mucociliary clearance (MC), electro-acupuncture (EA), needle puncture (NP), human neutrophil elastase (HNE), mucociliary transport velocity (MTV), phosphate buffered saline without Ca2+ and Mg2+ (PBS (-))

Competing interests

Localization (saline) of PBS in puncture associated with pulmonary disease and acupuncture
4) Confidence 0.14 Published 2006 Journal BMC Complement Altern Med Section Body Doc Link PMC1397865 Disease Relevance 0.56 Pain Relevance 0.30
On the following day, bees were assigned randomly to two groups and were injected with either emetine or PBS, and after 30?
Localization (emetine) of PBS
5) Confidence 0.11 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC3004282 Disease Relevance 0 Pain Relevance 0
In addition, in this case, the release medium, PBS pH 7.4, contributed to delaying the drug release due to the reduced solubility of chitosan hydrochloride at this pH.
Localization (release) of PBS
6) Confidence 0.10 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2901822 Disease Relevance 0 Pain Relevance 0.15
Drug release from liposomes into STF, pH 7.4 PBS, and five different modified tear formulations was also evaluated.
Localization (release) of PBS in tear
7) Confidence 0.08 Published 1998 Journal Drug Deliv Section Abstract Doc Link 19569989 Disease Relevance 0 Pain Relevance 0.07
The release kinetics of the entrapped agent seemed to be a biphasic process and the drug-release in both simulated tear fluid (STF) and pH 7.4 phosphate buffered saline (PBS) solutions followed pseudo first-order kinetics in the early stage of the release profile.
Localization (release) of PBS in tear
8) Confidence 0.08 Published 1998 Journal Drug Deliv Section Abstract Doc Link 19569989 Disease Relevance 0 Pain Relevance 0.06
After the drug treatment, cells were harvested, washed with PBS, and then lysed in ice-cold modified RIPA buffer (50?
Localization (washed) of PBS
9) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896885 Disease Relevance 0 Pain Relevance 0.08

General Comments

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