INT142605

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 2
SCs 2
H2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 45 91.44 High High
Neuritis 5 84.84 Quite High
Deep tissue 2 81.44 Quite High
Inflammation 1 63.68 Quite High
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 91.24 High High
Experimental Autoimmune Neuritis 5 84.84 Quite High
Syndrome 1 81.80 Quite High
Disorder Of Lipid Metabolism 2 75.00 Quite High
Autoimmune Disease 4 74.84 Quite High
INFLAMMATION 1 63.68 Quite High
Demyelinating Disease 3 62.64 Quite High
Animal Disease Models 1 46.96 Quite Low
Lymphatic System Cancer 3 25.44 Quite Low
Disease 5 5.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased MHC-II and CD40 expression on SCs was accompanied by lower levels of intracellular IL-6 production within SCs of apoE deficiency, which is confirmed by the neutralization with anti IL-6 antibody.
Regulation (accompanied) of Gene_expression (expression) of MHC-II in SCs
1) Confidence 0.15 Published 2007 Journal Glia Section Abstract Doc Link 17357152 Disease Relevance 0.90 Pain Relevance 0.42
Specifically, the expression levels of CD40, CD80, CD86 and MHC II were evaluated in unlabeled, SPIO-loaded and PMA-activated B cells via flow cytometry, Fig. 1D.
Regulation (evaluated) of Gene_expression (expression) of MHC II in B cells
2) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2871797 Disease Relevance 0.09 Pain Relevance 0.13

General Comments

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